how to Delete HUGE amount of data with out timing out

I have a table with a 44 Million records. With a PK of location. I am trying to delete a single location that has 1.5 million records. Delete from myBigTable where location = '01234' I have tried with and with out a Tran and still times out. what is the best approach on deleting HUGE amounts of data. Break it out some how ie Get count delete top 100000, next 100000 ect